1,新建word模版,方法是找需要用程序填充的word文檔,在需要輸入的地方用"書簽"(插入-->書簽-->輸入id-->ok)標記后保存既可. 
2,在word模版上修改安全添加everyone 可讀,以防文件無法打開. 
3,在工程里添加"引用"找到"Microsoft Word 10.0 Object Library"或"Microsoft Word 11.0 Object Library"點確定. 
4,新建類叫WordOp.cs 意思是操作word的類. 
內容如下: 

復制代碼代碼如下:

using System; 
using System.Web.Security; 
using Microsoft.Office.Interop.Word; 
using System.IO; 
/// <summary> 
/// Word 的摘要說明 
/// </summary> 
public class WordOp 
{ 
public WordOp() 
{ 
// 
// TODO: 在此處添加構造函數邏輯 
// 
} 
private ApplicationClass WordApp ; 
private Document WordDoc; 
private static bool isOpened=false;//判斷word模版是否被占用 
public void SaveAs(string strFileName,bool isReplace) 
{ 
if (isReplace && File.Exists(strFileName)) 
{ 
File.Delete(strFileName); 
} 
object missing = Type.Missing; 
object fileName = strFileName; 
WordDoc.SaveAs(ref fileName, ref missing, ref missing, ref missing, ref missing, ref missing, ref missing, 
ref missing, ref missing, ref missing, ref missing, ref missing, ref missing, ref missing, ref missing, ref missing); 
} 
//定義一個Word.Application 對象 
public void activeWordApp() 
{ 
WordApp = new ApplicationClass(); 
} 
public void Quit() 
{ 
object missing = System.Reflection.Missing.Value; 
WordApp.Application.Quit(ref missing, ref missing, ref missing); 
isOpened = false; 
} 
//基于模版新建Word文件 
public void OpenTempelte(string strTemppath) 
{ 
object Missing = Type.Missing; 
//object Missing = System.Reflection.Missing.Value; 
activeWordApp(); 
WordApp.Visible = false; 
object oTemplate = (object)strTemppath; 
try 
{ 
while (isOpened) 
{ 
System.Threading.Thread.Sleep(500); 
} 
WordDoc = WordApp.Documents.Add(ref oTemplate, ref Missing, ref Missing, ref Missing); 
isOpened = true; 
WordDoc.Activate(); 
} 
catch (Exception Ex) 
{ 
Quit(); 
isOpened = false; 
throw new Exception(Ex.Message); 
} 
} 
public void FillLable(string LabelId,string Content) 
{ 
//打開Word模版 
// OpenTempelte(tempName); //對LabelId的標簽進行填充內容Content,即函件題目項 
object bkmC = LabelId; 
if (WordApp.ActiveDocument.Bookmarks.Exists(LabelId) == true) 
{ 
WordApp.ActiveDocument.Bookmarks.get_Item(ref bkmC).Select(); 
} 
WordApp.Selection.TypeText(Content); 
//SaveAs(saveAsFileName); 
//Quit(); 
} 
} 

5,在需要使用的頁面后臺調用既可,舉例如下: 

復制代碼代碼如下:

string path = Server.MapPath("download"); 
string templatePath = path + "file://downloadczql.doc/"; 
WordOp wop = new WordOp(); 
wop.OpenTempelte(templatePath); 
wop.FillLable("id", "1"); 
wop.FillLable("usr_name", "測試"); 
wop.SaveAs(path + "file://savetest.doc",true/); 
wop.Quit(); 
Response.redirect(@"/download/savetest.doc");//做個跳轉用于下載.